Ginkgo Biloba Extract
1 General Description:
Specification Standards :
(1)Routine
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
(2) CP2005
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
Ginkgolic acid < 10ppm
(3) EGB761
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
Ginkgolic acid < 5ppm
(4) Minimal acid
Total Ginkgo flavone glycosides > 24%
Quercatin: kaemperol 0.8--1.5
Total terpene lactones > 6%
Ginkgolic acid < 1ppm
(5) Europe Standards
Total Ginkgo flavone glycosides 22-27%
Total terpene lactones 5-7%
G.A+G.B+G.C 2.8-3.4%
B.B 2.6-3.2%
Ginkgolic acid <5ppm;<1ppm
The quality specification of ginkgo biloba extract in CP2005:
Preparation: Withdraw under a reflux condenser of ethanol ,adsorb with macroporous resin, spray to dry, comminute.
Character: Yellowish brown to brownish powder, mildly bitter flavour
Test: Moisture<5.0%
Residue on ignition<0.8%
Heavy metal is not more than twenty millionths, namely less than 20ppm
The peak area ratio of flavonoid glycoside, namely Quercatin: kaemperol should be 0.8--1.5
Total ginkgo acid should be not more than ten millionths, namely 10ppm
Assay: High performance liquid chromatography
Total Ginkgo flavone glycosides >24%
The content of total ginkgo flavone glycosides is the sum of the content of quercatin, kaemperol and isorhamnetin (Quercatin: kaemperol 0.8-1.5. If it surpasses 1.5, it should be suspected to add quercatin.)
Total terpene lactones > 6%
The content of total terpene lactones is the sum of the content of bilobalide, ginkgolide A, B and C.
Function:
Promoting blood circulation, removing blood stasis and obstruction in the channels. It is indicated in the prevention and treatment of obstruction of Qi in chest and stroke induced by blood stasis with symptoms including chest pain, palpitations, stiff tongue, dysphasia or aphasia, hemiparalysis, coronary disease, angina pectoris, Cardiac infarction, cerebral coronary thrombembolia,etc.
it is widely used as the additive in health care products, foods, beverages and cosmetics etc.
2.Manufacturing Data:
Botanical Name : Ginkgo biloba L.
Part of plant used : leaves ;
Method of Manufacturing : maceration , reflux ;
Solvent for Extraction : Ethanol / water
Carrier / Excipient : none ;
Ratio of Botanical to Native Extract: 50:1
3.Quality Data :
Description: Yellowish brown to brownish powder;mildly bitter flavour ;
Particle Size : 80 mesh
Loss on Drying: Not more than 5%
Heavy Metals <20ppm
4.Microbiological Inspection :
Total Plate Count <1000cfu/g
Total Mold Count <100cfu/g
E. Coli Negative
Live Mite Negative
5.Manufacture:
Ningbo Dekang Biochem Co., Ltd.
Mr. ArthurLi
Tel:+86-574-81625959,13566347633 fax +86-574-83033289
E-mail: liqingliang_2008@.cn, MSN:hy651025@
銀杏葉提取物 Ginkgo Biloba Extract
1 General Description/概述：
Specification Standards /規(guī)格標準：
我公司可供應以下規(guī)格：
（1）常規(guī)產(chǎn)品（未處理銀杏酸）
銀杏黃酮 ≥24%
槲皮素與山奈酚峰比0.8- -1.5之間
銀杏總內(nèi)酯≥6%
（2）中國藥典2005版標準
銀杏黃酮 ≥24%
槲皮素與山奈酚峰比0.8- -1.5之間
銀杏總內(nèi)酯≥6%
銀杏酸 ＜10ppm
(3) 低酸銀杏葉提取物 EGB761
銀杏黃酮 ≥24%
槲皮素與山奈酚峰比0.8- -1.5之間
銀杏總內(nèi)酯≥6%
銀杏酸 ＜5ppm
（4）超低酸銀杏葉提取物
銀杏黃酮 ≥24%
槲皮素與山奈酚峰比0.8- -1.5之間
銀杏總內(nèi)酯≥6%
銀杏酸 ＜1ppm
5、歐洲標準銀杏葉提取物
銀杏黃酮22-27%，
銀杏總內(nèi)酯5-7%
G.A+G.B+G.C 2.8-3.4%
B.B 2.6-3.2%
銀杏酸<5ppm;<1ppm
2005版中國藥典銀杏葉提取物質(zhì)量標準：
制法：乙醇回流提取，大孔樹脂吸附，噴幹，粉碎。
性狀：淺棕黃色至棕褐色粉末；味微苦。
檢查：水分小於5.0%；
熾灼殘渣小於0.8%；
重金屬不得過百萬分之二十，即20ppm以下。
黃酮苷元峰面積比，槲皮素與山奈素的峰面積比應為0.8至1.5。
總銀杏酸不得過百萬分之十，即10ppm。
含量測定：高效液相色譜法。
總黃酮醇苷不得少於24.0%；
總黃酮醇苷含量=槲皮素含量+山奈素含量+異鼠李素含量。（槲皮素與山奈素的峰面積比應為0.8至1.5之間。如果超過1.5，則應懷疑被人為添加了槲皮素。）
萜類內(nèi)脂總量不得少於6.0%；
萜類內(nèi)脂總量=白果內(nèi)脂+銀杏內(nèi)脂A+銀杏內(nèi)脂B+銀杏內(nèi)脂C。
Function /功效：
活血化瘀、通脈舒絡、益氣健腦。主要用於腦部，周邊血流迴圈障礙。
適應癥：
1.急慢性腦機能不全，注意力不集中，記憶力衰退，老年癡呆，及腦血管硬化癥狀，中風後遺癥。
2.耳部之血流及神經(jīng)障礙，如耳鳴、眩暈和突聾。
3.眼部之血流及神經(jīng)障礙，如糖尿病視網(wǎng)膜病變和老年黃斑部退化。
4.末稍迴圈障礙，如周邊動脈阻塞癥，間歇破行癥和手、腳的冰冷麻痹。
2.Manufacturing Data /生產(chǎn)資料：
Botanical Name / 植物名：銀杏 Ginkgo biloba L.
Part of plant used /使用部位：葉
Method of Manufacturing /生產(chǎn)方法：maceration reflux
Solvent for Extraction /提取溶劑：Ethanol / water
Carrier / Excipient /輔料/ 賦型劑：無
Ratio of Botanical to Native Extract /原材料與提取物比率：50：1
3.Quality Data /質(zhì)量數(shù)據(jù)：
Description/性狀：淺棕黃色至棕褐色粉末；味微苦。
Particle Size /粉末細度： 80 mesh
Loss on Drying /乾燥失重：Not more than 5%
Heavy Metals /重金屬：≤20ppm
4.Microbiological Inspection / 微生物：
Total Plate Count ＜1000cfu/g
Total Mold Count ＜100cfu/g
E. Coli Negative
Live Mite Negative
5.Manufacture/生產(chǎn)商:
寧波德康生物 李慶良
Tel:+86-574-81625959,13566347633 fax +86-574-83033289
E-mail: liqingliang_2008@.cn MSN:hy651025@